Molecular Principles of RNA-based Regulation
On Thursday, 15.11.2018, 5.15 pm
„Transcriptome changes caused by toxic RNA in myotonic dystrophy“.Venue: TU Darmstadt, Campus Botanischer Garten, lecture hall: B101/52
Dear friends of RNA,
we are happy to announce the 5. RMU-RNA Salon event “Genomics approaches in RNA Biology”.
The RMU-RNA Salon is designed as a series of mini-symposia to bring together scientists interested in RNA biology within the Rhine-Main area to increase the awareness for available methods and to fuel the interactions:
When: Wednesday, October 24th 2018, 12:30 am – 6:30 pm
Where: Biomedizinisches Forschungszentrum (BMFZ) Marburg
Keynote:
Katja Strässer (IBC, JLU Gießen) – mRNA packaging & export
Presenting groups:
Arnold Grünweller (IPC, PU Marburg) – RNA viruses
Aline Koch (IPP, JLU Gießen) – RNAi in plants
Julien Bethune (BZH, Uni Heidelberg) – RBPs & endomembranes
Andreas Krueger (IMM, GU Frankfurt) – miRNAs & T-cell development
Marcel Schulz (ICR, GU Frankfurt) – Systems Biology
Jennifer Winter (IHG, JGU Mainz) – miRNAs & neuronal development
Please register for free at http://bit.do/RMU-RNA-Salon5 !
We cordially invite you to present your own research and meet with the speakers.
Abstracts for short talks and posters are welcome!
Next week – on Friday, 7th September 2018, 12:30 h s.t.
N.S. Qureshi, S. Sreeramulu, J.K. Bains, H. Schwalbe*, B. Fürtig*
Nucleic Acids Res. in press
H. Keller, A. K. Weickhmann, T. Bock, J. Wöhnert.
RNA. 2018
Full publication here: Adenine protonation enables cyclic-di-GMP binding to cyclic-GAMP sensing riboswitches.
Abstract: Read more …
M. Krepl, J. Vögele, H. Kruse, E. Duchardt-Ferner, J. Wöhnert, J.
Sponer.
Nucleic Acids Res. 2018
Full publication here: An intricate balance of hydrogen bonding, ion atmosphere and dynamics facilitates a seamless uracil to cytosine substitution in the U-turn of the neomycin-sensing riboswitch
Abstract: Read more …
C. Voigt, M. Dobrychłop, E. Kruse, A. Czerwoniec, J. M. Kasprzak, P. Bytner, C. Del Campo, W-M. Leeder, J. M. Bujnicki, H. U. Göringer.
Nucleic Acids Research. 2018
Full publication here: The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity
Abstract: Read more …
The biology of ribonucleoprotein particles (RNPs) is an important and quickly expanding area of current life science research. Especially for young and less experienced researchers in this field it is often difficult to keep an overview over and to identify and select the optimal combination of analytical tools required to solve their various questions.
Therefore, the Graduate Research Academy RNA Biology organizes a practical course for PhD students with the aim to introduce the participants to a selection of innovative new approaches and state-of-the-art methodology in RNP biology research. Participants will receive hands-on training by renowned experts in the field and have the possibility to discuss their own research projects with invited speakers and local experts to further their own research projects.
In addition to the scientific excellence of the invited speakers the practical course builds on a strong local methodological expertise since all of the presented techniques are actively used by at least one research team within the Collaborative Research Center SFB960 (www.sfb960.de).
The practical course “From Ensembles to Single-Molecule Analysis – Modern Methods of RNP Analysis” will take place from 8 to 12 October 2018 in Regensburg. Course attendance is free. Registration deadline is 15 July 2018.
For further information and for registration please visit following website: https://www.rnabiology-regensburg.de/index.php?browse=150
Schwalbe H, Keyhani S, Goldau T, Blümler A, Heckel A.
Angew Chem Int Ed Engl. 2018
Full publication here: Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy.
Abstract: Read more …
Deußner-Helfmann NS, Auer A, Strauss MT, Malkusch S, Dietz MS, Barth HD, Jungmann R, Heilemann M.
Nano Lett. 2018
Full publication here: Correlative Single-Molecule FRET and DNA-PAINT Imaging
Abstract: Read more …
4. Mini-Symposium “Molecular mechanisms of posttranscriptional regulation” on methods to study processing, structure, and translation of mRNAs as well as non-coding RNAs in disease-related contexts.
Keynote Speaker:
Guest speaker:
more information available on the Homepage of the IMB, Mainz
RNA – Chemistry and Architecture
May 21—25 | 2018
more info: Sammet Homepage of the Goethe University
Konrad Förstner, Head of the Core Unit Systems Medicine
Julius-Maximilians-Universität Würzburg will give a talk titled:
Translating high-throughput sequencing data into biological insights
Thursday, 03th May 2018
17.15 pm
Technische Universität Darmstadt
Campus Botanischer Garten, N101/lecture hall 52
On April 16th 6 17th, all PIs of the SFB 902 are presenting and discussing their ideas and projects for the 3rd SFB 902 funding period.
April, 16th: 11 am, Biozentrum Campus Riedberg, N100/0.15
April 17th: 11 am, Biozentrum Campus Riedberg, N100/B3
Kwaku Dayie
University of Maryland
What is the big deal about ‘invisible’ RNA conformational states in Biology?
Thursday, 29th March 2018
4.00 pm
Goethe-University Frankfurt
Campus Riedberg, N100/lecture hall B2
Dr. Sabine Brantl
AG Bakteriengenetik, Universität Jena
Small RNAs and small peptides
Tuesday, 27th March 2018
3.00 pm
Goethe-University Frankfurt
Campus Riedberg, N100/lecture hall B2
The 5th Meeting of Regulating with RNA in Bacteria & Archaea
will take place in
March 19-22, 2018 • Seville/Spain
more information here
This year’s Winter School will take place in Altglashütten, Schwarzwald, from March 4th to 8th.
Exciting talks, fun in the snow and intensive interactions will hopefully lead to an enjoyable event and, eventually, to successful PhD projects
Please register here
Dear friends of RNA,
we are happy to announce the third edition of our EMBO course “iCLIP: Genomic views of protein-RNA interactions’, which will take place at the CRG in Barcelona from June 3rd to June 9th, 2018.
The course is targeted to Junior researchers (mainly PhDs and Postdocs) who are interested in Protein/RNA interactions.
We would be grateful if you could forward this email to interested colleagues.
Registration deadline is March 1st 2018.
You can find more info about the course here
Dear friends of RNA,
The next RNA Club will take place on February, 28th at 5 pm.
Room and program will be announced soon (www.rnaclub.de).
We hope to see you there and discuss over beer and Pizza.
Michaela & Beatrix
contact for more info:
Michaela Müller-McNicoll (Ph.D.)
http://www.bio.uni-frankfurt.de/52678296/Group
Dr. Zasha Weinberg
Department of Computer Science, Leipzig University
Computational discovery of novel classes of bacterial non-coding RNAs
Thursday, 8th February 2018
12.30 pm
TU Darmstadt, lecture hall: B261/102
Abstract: The discovery of new classes of non-coding RNAs (ncRNAs) can reveal information about the biological processes that involve these ncRNAs as well as yielding general insights into RNA biochemistry and gene regulation. Riboswitch RNAs directly sense a metabolite and regulate genes accordingly. We devised a strategy to find riboswitches that have evolved specificity to a new metabolite ligand. Such specificity changes are well known in proteins, but only a few examples are known in RNA. I will also describe a more general search strategy for novel structured ncRNAs on a multi-genome/metagenome scale. This search revealed 224 novel ncRNAs of various types. I will also show computational predictions that have been experimentally confirmed.
Gophane DB, Endeward B, Prisner T F, and Sigurdsson ST.
Org. Biomol. Chem, 2018 Advance Article.
Full publication here: A semi-rigid isoindoline-derived nitroxide spin label for RNA
Abstract: Read more …
Groher F, Bofill-Bosch C, Schneider C, raun J, Jager S, Geißler K, Hamacher K, Süß B.
Nucleic Acids Research, 2018 Jan 13.
Full publication here: Riboswitching with ciprofloxacin—development and characterization of a novel RNA regulator
Abstract: Read more …