A8: Mike Heilemann

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Institut für Physikalische und Theoretische Chemie
N120 / 1. OG / Raum Nr. 1.24
Goethe-University Frankfurt am Main
Max-von-Laue-Str. 7
60438 Frankfurt am Main,
Phone +49 (0)69 798-29736
Homepage AK Heilemann
Mike Heilemann-

Personal data

Date of birth 02/01/1976


1996-2001 Diploma in Chemistry, Heidelberg University
2002-05 Ph.D. in Physics, Bielefeld University

Research Experience

2005-07 Postdoctoral Fellow with Dr. A. Kapanidis, University of Oxford, UK
2007-11 Junior Group Leader, Physics Department, Bielefeld University, Germany
2011-12 Assistant Professor (W2) for Biophysics, University of Würzburg, Germany
2012- Full Professor (W3), Goethe-University Frankfurt, Institute of Physical and Theoretical Chemistry, Germany
2013 Overseas Visiting Scholar, St John’s College, Cambridge University

Honors and Awards

2001-02 Egide fellowship
2006-07 DAAD fellowship
2008-13 BMBF junior research group, FORSYS program (1.5 Mio€)
2012 EPA-PPA paper prize, European Photochemistry Association
2013 St. John’s Oversea Fellowship, University of Cambridge, UK

Ten most relevant publications (2009-2014)

Endesfelder U & Heilemann M (2014) Art and artifacts in single-molecule localization microscopy: beyond attractive images. Nat. Methods 11: 235–8. Available at: http://dx.doi.org/10.1038/nmeth.2852.
Spahn C, Endesfelder U & Heilemann M (2014) Super-resolution imaging of Escherichia coli nucleoids reveals highly structured and asymmetric segregation during fast growth. J. Struct. Biol. 185: 243–9. Available at: http://dx.doi.org/10.1016/j.jsb.2014.01.007.
Endesfelder U, Finan K, Holden SJ, Cook PR, Kapanidis AN & Heilemann M (2013) Multiscale spatial organization of RNA polymerase in Escherichia coli. Biophys. J. 105: 172–81 Available at http://dx.doi.org/10.1016/j.bpj.2013.05.048.
Perkovic M, Kunz M, Endesfelder U, Bunse S, Wigge C, Yu Z, Hodirnau V-V, Scheffer MP, Seybert A, Malkusch S, Schuman EM, Heilemann M & Frangakis AS (2014) Correlative Light- and Electron Microscopy with chemical tags. J. Struct. Biol. 186: 205–13 Available at http://dx.doi.org/10.1016/j.jsb.2014.03.018.
Muranyi W, Malkusch S, Müller B, Heilemann M & Kräusslich H-G (2013) Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail. PLoS Pathog. 9: e1003198 Available at http://dx.doi.org/10.1371/journal.ppat.1003198.
Heidbreder M, Zander C, Malkusch S, Widera D, Kaltschmidt B, Kaltschmidt C, Nair D, Choquet D, Sibarita J-B & Heilemann M (2012) TNF-α influences the lateral dynamics of TNF receptor I in living cells. Biochim. Biophys. Acta 1823: 1984–9 Available at http://dx.doi.org/10.1016/j.bbamcr.2012.06.026.
Malkusch S, Muranyi W, Müller B, Kräusslich H-G & Heilemann M (2013) Single-molecule coordinate-based analysis of the morphology of HIV-1 assembly sites with near-molecular spatial resolution. Histochem. Cell Biol. 139: 173–9 Available at http://dx.doi.org/10.1007/s00418-012-1014-4.
Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM, Sauer M, Allshire RC, Heilemann M & Laue ED (2012) Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast. Open Biol. 2: 120078 Available at http://dx.doi.org/10.1098/rsob.120078.
Wombacher R, Heidbreder M, van de Linde S, Sheetz MP, Heilemann M, Cornish VW & Sauer M (2010) Live-cell super-resolution imaging with trimethoprim conjugates. Nat. Methods 7: 717–9 Available at http://dx.doi.org/10.1038/nmeth.1489.
Heilemann M, van de Linde S, Mukherjee A & Sauer M (2009) Super-resolution imaging with small organic fluorophores. Angew. Chem. Int. Ed. 48: 6903–8 Available at http://dx.doi.org/10.1002/anie.200902073.