B7: Robert Tampé

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Institut für Biochemie
N210 / Raum Nr. 1.01
Goethe-University Frankfurt am Main
Max-von-Laue-Str. 9
60438 Frankfurt am Main, Germany
Phone +49 (0)69 798-29475
Homepage AK Tampé
Robert Tampé

Personal data

Date/Place of birth 08/14/1961 in Seligenstadt


1981-1987 Diploma (Chemistry), TU Darmstadt
1987-1989 Ph.D. (Biochemistry) with Prof. Dr. H.J. Galla, TU Darmstadt
1990-1991 Postdoctoral Fellow with Prof. Dr. H.M. McConnell, Stanford, CA

Research Experience

1992-1998 Junior Group Leader, Max-Planck-Institute of Biochemistry, Martinsried/Munich, Germany
1992-1998 Group Leader, Biophysics Department, TU Munich, Germany
1996 Habilitation (Biochemistry), TU Munich, Germany
1996-1998 Assistant Professor for Biochemistry/Biophysics, TU Munich, Germany
1998-2001 Full Professor & Director, Institute of Physiological Chemistry, Medical Faculty, Philipps-University Marburg, Germany
2001 Full Professor & Director, Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Germany
2003-07 Speaker of the SFB 628 – Functional Membrane Proteomics
2007 Cofounder and Principal Investigator of the Cluster of Excellence Frankfurt (CEF) – Macromolecular Complexes
2008 Speaker of the SFB 807 – Membrane Transport and Communication
2009 Adjunct Professor at University of California San Francisco, U.S.A.
2010 Guest Professor, iCeMS, Kyoto University, Japan

Honors and Awards

2014 Liaison officer German Research Foundation (DFG)
2010- Honorary Visiting Professor, iCeMS, Kyoto University, Japan
2010- Chair, Paul-Ehrlich Young Investigator Award (Paul-Ehrlich Foundation)
2009-2010 Guest Professor, University of California San Francisco (UCSF)
2007-2010 Editorial Board Member, The Journal of Biological Chemistry (ASBMB)
2012 Teaching Excellence in Biochemistry
2010 & 2011 Award: Best Teaching in Biochemistry
2001-03 Editor of Faculty 1000
1998-2001 Liaison officer of Studienstiftung des Deutschen Volkes
1996-98 Heisenberg Fellow, DFG
1989-91 Postdoctoral Fellowship of DFG and Max-Kade Foundation (New York)
1989 Ph.D. in Biochemistry, summa cum laude
1987-89 Doctoral Fellowship, Fonds der Chemischen Industrie (FCI)
1987 Diploma in Chemistry, summa cum laude
1985 Anton Keller Prize in Chemistry
1984-87 Fellowship, Studienstiftung des Deutschen Volkes
1983-87 Fellowship, Cusanuswerk

Ten most relevant publications (2009-2014)

Kim JM, Wu, S, Tomasiak T, Mergel C, Winter MN, Stiller S, Robles-Colmanares Y, Stroud RM*, Tampé R*, Craik CS*, Cheng Y* (2014) Subnanometer resolution cryo-EM structure of a nucleotide free heterodimeric ABC exporter. Nature, 517: 396–400. Available at http://dx.doi.org/10.1038/nature13872 (*shared corresponding authorship).
Gatterdam V, Ramadass R, Stoess T, Fichte MAH, Wachtveitl J, Heckel A & Tampé R (2014) Three-dimensional protein networks assembled by two-photon activation. Angew. Chem. Int. Ed. 53: 5680–4. Available at http://dx.doi.org/10.1002/anie.201309930.
Urban M, Kleefen A, Mukherjee N, Seelheim P, Windschiegl B, Vor der Brüggen M, Koçer A & Tampé R (2014) Highly parallel transport recordings on a membrane-on-nanopore chip at single molecule resolution. Nano Lett. 14: 1674–80. Available at http://dx.doi.org/10.1021/nl5002873.
Labòria N, Wieneke R & Tampé R (2013) Control of nanomolar interaction and in situ assembly of proteins in four dimensions by light. Angew. Chem. Int. Ed. 52: 848–53. Available at http://dx.doi.org/10.1002/anie.201206698.
Wei R, Gatterdam V, Wieneke R, Tampé R* & Rant U* (2012) Stochastic sensing of proteins with receptor-modified solid-state nanopores. Nat. Nanotechnol. 7: 257–63. Available at http://dx.doi.org/10.1038/nnano.2012.24 (*shared corresponding authorship).
Hulpke S, Baldauf C & Tampé R (2012) Molecular architecture of the MHC I peptide-loading complex: one tapasin molecule is essential and sufficient for antigen processing. FASEB J. 26: 5071–80. Available at http://dx.doi.org/10.1096/fj.12-217489.
Barthelme D, Dinkelaker S, Albers S-V, Londei P, Ermler U & Tampé R (2011) Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1. Proc. Natl. Acad. Sci. U. S. A. 108: 3228–33. Available at http://dx.doi.org/10.1073/pnas.1015953108.
Herget M, Baldauf C, Schölz C, Parcej D, Wiesmüller K-H, Tampé R, Abele R & Bordignon E (2011) Conformation of peptides bound to the transporter associated with antigen processing (TAP). Proc. Natl. Acad. Sci. U. S. A. 108: 1349–54. Available at http://dx.doi.org/10.1073/pnas.1012355108.
Baldauf C, Schrodt S, Herget M, Koch J & Tampé R (2010) Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation. Proc. Natl. Acad. Sci. U. S. A. 107: 9135–40. Available at http://dx.doi.org/10.1073/pnas.1001308107.
Grunwald C, Schulze K, Reichel A, Weiss VU, Blaas D, Piehler J, Wiesmüller K-H & Tampé R (2010) In situ assembly of macromolecular complexes triggered by light. Proc. Natl. Acad. Sci. U. S. A. 107: 6146–51. Available at http://dx.doi.org/10.1073/pnas.0912617107.