A09 – Gerhard Hummer

Molecular Simulations of RNA Folding and Function

The aims of this project are (I) to advance the methods of RNA molecular simulations, and (II) to use these methods to explore RNA folding, dynamics, and function. In close collaboration with the experimental projects, the properties of riboswitches will be examined to identify their molecular mechanisms. Molecular simulations will also be used to optimize photoswitches, spin labels, and other RNA modifications used in the experiments. The simulations thus help both in the interpretation of complex RNA experiments, and in their design.


Gerhard Hummer (Principal Investigator)
Lukas Stelzl
Marcel Heinz 

Nadine Schwierz-Neumann (Associated Principal Investigator)

Kara Grotz