Sonderforschungsbereich 902

Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy.

Schwalbe H, Keyhani S, Goldau T, Blümler A, Heckel A.
Angew Chem Int Ed Engl. 2018

Full publication here: Chemo-enzymatic synthesis of position-specifically modified RNA for biophysical studies including light control and NMR spectroscopy.

Abstract:  Read more …

Activity-dependent spatially localized miRNA maturation in neuronal dendrites

Sambandan S, Akbalik G, Kochen L, Rinne J, Kahlstatt J, Glock C, Tushev G, Alvarez-Castelao B, Heckel A, Schuman EM
Science. 2017 Feb 10. Abstract   Read more …

Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.

Thevarpadam J, Bessi I, Binas O, Gonçalves DP, Slavov C, Jonker HR, Richter C, Wachtveitl J, Schwalbe H, Heckel A. Angew Chem Int Ed Engl. 2016 Feb 18. Abstract  Read more …

Ultrafast Spectroscopy of Hydroxy-Substituted Azobenzenes in Water.

Steinwand S, Halbritter T, Rastädter D, Ortiz-Sánchez JM, Burghardt I, Heckel A, Wachtveitl J. Chemistry. 2015 Oct 26. Abstract Read more …

Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside.

Goldau T, Murayama K, Brieke C, Steinwand S, Mondal P, Biswas M, Burghardt I, Wachtveitl J, Asanuma H, Heckel A. Chemistry. 2015 Feb 9. Abstract Read more …

Three-dimensional protein networks assembled by two-photon activation.

Gatterdam V, Ramadass R, Stoess T, Fichte MA, Wachtveitl J, Heckel A, Tampé R. Angew Chem Int Ed Engl. 2014 May 26. Abstract Read more …

Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability.

Steinert HS, Schäfer F, Jonker HR, Heckel A, Schwalbe H. Angew Chem Int Ed Engl, 2014 Jan 20. Abstract Read more …

Characterization of the conformational dynamics of bistable RNAs by equilibrium and non-equilibrium NMR methods.

Fürtig B, Reining A, Sochor F, Oberhauser EM, Heckel A, Schwalbe H. Curr. Prot. in Nucl. Acid Chem., 2013 Dec. Abstract Read more …

Spiropyran Photoswitches in the Context of DNA: Synthesis and Photochromic Properties.

Brieke C, Heckel A. Chemistry. 2013 Nov 11. Abstract Read more …

Aptamer-guided caging for selective masking of protein domains.

Rohrbach F1, Schäfer F, Fichte MA, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. Angew Chem Int Ed Engl. 2013 Nov 4. Abstract Read more …

Regulation der Angiogenese durch lichtinduzierbare AntimiRs.

Schäfer F, Wagner J, Knau A, Dimmeler S, Heckel A. Angew Chem 2013 Oct 31. Abstract Read more …

Rapid synthetic access to caged RNA.

Rodrigues-Correia A, Stoess T, Wilhelm J, Berlin B, Heckel A. IJC-A. 2013 Aug. Abstract Read more …

Ultrafast Dynamics of a Spiropyran in Water.

Kohl-Landgraf J, Braun M, Ozçoban C, Gonçalves DP, Heckel A, Wachtveitl J. J Am Chem Soc, 2012 August 14. Abstract Read more …

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.

Wurm JP, Griese M, Bahr U, Held M, Heckel A, Karas M, Soppa J, Wöhnert J. RNA, 2012 Jan 24. Abstract Read more …